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Image Search Results
Journal: Scientific Reports
Article Title: Comparative analysis of cutaneous features of psoriasis in acute and chronic imiquimod-induced mouse models
doi: 10.1038/s41598-025-12111-6
Figure Lengend Snippet: Effects of IMQ on the gene expression levels of pro-inflammatory mediators and epidermal markers after ST and LT treatments. Pro-inflammatory mediators (IL-17A ( A ), IL-1α ( B ), CXCL3 ( C )), AMPs (BD3 ( D )) and epidermal markers (KRT6 ( E ), KRT10 ( F ), IVL ( G ), KLK5 ( H )) gene expression was assessed by RT-qPCR on total mRNAs from mouse back skin collected 24 h after the last Vaseline or IMQ application, and normalized with GAPDH (ST-Vaseline n = 25, ST-IMQ n = 32, LT-Vaseline n = 28, LT-IMQ n = 26). A Two-Way ANOVA with Bonferroni’s correction was performed to compare each mediator expression after ST and LT treatments either with Vaseline or IMQ.
Article Snippet: Quantitative PCR was conducted using the
Techniques: Gene Expression, Quantitative RT-PCR, Expressing